PERIODONTAL CONDITION OF EPILEPTIC ADULTS TREATED LONG-TERM WITH PHENYTOIN OR CARBAMAZEPINE

The periodontal condition of 40 adult epileptic subjects (mean age 51 years) receiving long-term therapy (mean 18 years) with phenytoin (PHT ) or carbamazepine (CBZ) was studied. The subjects completed a questio nnaire and underwent clinical and radiologic examination. Patients rec eiving PHT exhibited the same level of alveolar bone loss as those rec eiving CBZ. Patients receiving PHT exhibited more units with gingival overgrowth, reflected by the significantly higher number of gingival u nits with increased probing depth (p < 0.05). The results indicate tha t long-term PHT does not result in increased fisk for alveolar bone lo ss as compared with CBZ.