REACTIONS OF COBALT-COMPLEXED ACETYLENIC ALDEHYDES WITH CHIRAL (GAMMA-ALKOXYALLYL)BORANES - ENANTIOSELECTIVE SYNTHESIS OF 3,4-DIOXY 1,5-ENYNES

Authors
GANESH P NICHOLAS KM
Citation
P. Ganesh et Km. Nicholas, REACTIONS OF COBALT-COMPLEXED ACETYLENIC ALDEHYDES WITH CHIRAL (GAMMA-ALKOXYALLYL)BORANES - ENANTIOSELECTIVE SYNTHESIS OF 3,4-DIOXY 1,5-ENYNES, Journal of organic chemistry, 58(21), 1993, pp. 5587-5588
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
21
Year of publication
1993
Pages
5587 - 5588
Database
ISI
SICI code
0022-3263(1993)58:21<5587:ROCAAW>2.0.ZU;2-L
Abstract
Whereas free acetylenic aldehydes react with (gamma-alkoxyallyl)diisoc ampheylboranes 3 with poor efficiency (<10% yield) and limited enantio selectivity, the corresponding -Co2(CO)6 complexes 1 undergo efficient (65-76% yield), diastereoselective (88->95% de), and enantioselective (>96% ee) coupling reactions with 3, producing (3,4-dioxy 1,5-enyne)C o2(CO)6 4.