CONSIDERATION OF CHEMICAL MECHANISMS FOR THE NONPHOTOCHEMICAL PRODUCTION OF VITAMIN-D3 IN BIOLOGICAL-SYSTEMS

Authors
NORMAN TC NORMAN AW
Citation
Tc. Norman et Aw. Norman, CONSIDERATION OF CHEMICAL MECHANISMS FOR THE NONPHOTOCHEMICAL PRODUCTION OF VITAMIN-D3 IN BIOLOGICAL-SYSTEMS, Bioorganic & medicinal chemistry letters, 3(9), 1993, pp. 1785-1788
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
9
Year of publication
1993
Pages
1785 - 1788
Database
ISI
SICI code
0960-894X(1993)3:9<1785:COCMFT>2.0.ZU;2-9
Abstract
Although most higher animals rely upon sunlight to convert 7-dehydroch olesterol into the prohormone vitamin D3, the mechanism(s) by which fi sh and subterranean animals generate this seco steroid are presently u nknown. This article proposes four nonphotochemical mechanisms which c ould be operative in appropriate biological systems to support the pro duction of this essential hormone.