CONFORMATIONAL-ANALYSIS OF DISUBSTITUTED SIDE-CHAIN OF VITAMIN-D3 ANALOGS - MOLECULAR MODELING AND SEMIEMPIRICAL CALCULATIONS

Authors
KUTNER A CHOLINSKI J CHODYNSKI M HALKES SJ
Citation
A. Kutner et al., CONFORMATIONAL-ANALYSIS OF DISUBSTITUTED SIDE-CHAIN OF VITAMIN-D3 ANALOGS - MOLECULAR MODELING AND SEMIEMPIRICAL CALCULATIONS, Bioorganic & medicinal chemistry letters, 3(9), 1993, pp. 1795-1798
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
9
Year of publication
1993
Pages
1795 - 1798
Database
ISI
SICI code
0960-894X(1993)3:9<1795:CODSOV>2.0.ZU;2-9
Abstract
The least-energy conformers were determined for side-chain disubstitut ed analogs of vitamin D3 by molecular mechanics modeling and semiempir ical calculations based on a generalized Karplus equation.