THE MICROBIOLOGY OF ACUTE DIARRHEAL DISEASE IN THE EASTERN PROVINCE OF SAUDI-ARABIA

A prospective study of acute diarrhoeal diseases in the Eastern Provin ce of Saudi Arabia was carried out over a 19-month period to determine aetiology, risk factors and other epidemiological characteristics. Of the 853 subjects studied, 344 were cases and 509 controls. More cases were seen in children than in adults. Enteric pathogens were detected in 49% of the cases, but none in the controls. Of the pathogens, 68% were bacterial with Salmonella (34%) and Shigella species (14.7%) bein g the most common; Campylobacter jejuni emerged as an important cause especially in adults. Contrary to most reports, rotaviruses were respo nsible for only 11.5% of the cases in children. Entamoeba histolytica (13.5%) and Giardia intestinalis (10.4%) were parasites commonly detec ted. Shigella organisms were the only pathogens that were isolated in hospital cases without being isolated in cases from the community.