IS SKEWED X-INACTIVATION RESPONSIBLE FOR SYMPTOMS IN FEMALE CARRIERS FOR ADRENOLEUKODYSTROPHY

Authors
WATKISS E WEBB T BUNDEY S
Citation
E. Watkiss et al., IS SKEWED X-INACTIVATION RESPONSIBLE FOR SYMPTOMS IN FEMALE CARRIERS FOR ADRENOLEUKODYSTROPHY, Journal of Medical Genetics, 30(8), 1993, pp. 651-654
Citations number
22
Categorie Soggetti
Genetics & Heredity
Journal title
Journal of Medical Genetics → ACNP
ISSN journal
00222593
Volume
30
Issue
8
Year of publication
1993
Pages
651 - 654
Database
ISI
SICI code
0022-2593(1993)30:8<651:ISXRFS>2.0.ZU;2-N
Abstract
A study of X inactivation in 12 female carriers for adrenoleucodystrop hy showed no evidence that skewed patterns are related to clinical man ifestation. Other possible mechanisms to explain manifestation in fema les are considered.