SYNTHESIS AND CHARACTERIZATION OF A SERIES OF HYDROPHOBIC ANTITUMOR BIS(CARBOXYLATO) (1,2-DIAMINOCYCLOHEXANE) PLATINUM(II) COMPLEXES

Authors
ALBAKER S PEREZSOLER R KHOKHAR AR
Citation
S. Albaker et al., SYNTHESIS AND CHARACTERIZATION OF A SERIES OF HYDROPHOBIC ANTITUMOR BIS(CARBOXYLATO) (1,2-DIAMINOCYCLOHEXANE) PLATINUM(II) COMPLEXES, Journal of coordination chemistry, 29(1-2), 1993, pp. 1-6
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of coordination chemistry → ACNP
ISSN journal
00958972
Volume
29
Issue
1-2
Year of publication
1993
Part
A
Pages
1 - 6
Database
ISI
SICI code
0095-8972(1993)29:1-2<1:SACOAS>2.0.ZU;2-K
Abstract
A series of hydrophobic platinum(II) complexes of the type (DACH)PtX2 (where DACH = various isomeric forms of 1,2-diaminocyclohexane and X=p entanoato, hexanoato, heptanoato, octanoato, nonanoato, decanoato, uni decanoato, laurato, tridecanoato, myristato, pentadecanoato, palmitato , heptadecanoato, or stearato) has been synthesized and characterized using elemental analysis, infrared spectra and nuclear magnetic resona nce (C-13{H-1} and Pt-195{H-1}). The complexes have been prepared as p otential antitumor agents for liposome entrapment.