INTENSIVE SURVEY OF ADVERSE DRUG-REACTION S OVER 1 YEAR IN A CARDIOLOGY DEPARTMENT

An intensive pharmacovigilance survey was carried out over the course of 1 year in cardiology department which revealed 64 reports of advers e drug reactions among 61 hospitalised patients, giving an overall inc idence of 2,3%. Most of the patients in whom adverse drug reactions we re recorded were elderly and female. The most common adverse events we re cardiovascular (72%) and haemorrhagic (9%), and related to drugs gi ven for the treatment of cardiovascular disorders. The symptoms origin ating from drug therapy were dominated by sinus arrhythmias (25 cases) , linked to drugs co-administered that have potentially similar cardia c pharmacodynamic effects. Seven cases of ''torsades de pointe'' were also observed.