ASYMMETRIC-SYNTHESIS VIA HETEROCYCLIC INTERMEDIATES .52. SYNTHESIS OFTERT-LEUCINE AND RELATED AMINO-ACIDS

Authors
GROTH U HUHN T PORSCH B SCHMECK C SCHOLLKOPF U
Citation
U. Groth et al., ASYMMETRIC-SYNTHESIS VIA HETEROCYCLIC INTERMEDIATES .52. SYNTHESIS OFTERT-LEUCINE AND RELATED AMINO-ACIDS, Liebigs Annalen der Chemie, (7), 1993, pp. 715-719
Citations number
21
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen der Chemie → ACNP
ISSN journal
01702041
Issue
7
Year of publication
1993
Pages
715 - 719
Database
ISI
SICI code
0170-2041(1993):7<715:AVHI.S>2.0.ZU;2-7
Abstract
The 2,5-dialkoxypyrazines 3a and b were prepared in three steps from m ethyl glycinate hydrochloride (1) in an overall yield of 18 and 63%. U pon the addition of lithium organyls to 3b and subsequent acidic hydro lysis the ethyl glycinates rac-7 were obtained.