M. Witsenburg et al., BALLOON ANGIOPLASTY FOR AORTIC RECOARCTATION IN CHILDREN - INITIAL AND FOLLOW-UP RESULTS AND MIDTERM EFFECT ON BLOOD-PRESSURE, British Heart Journal, 70(2), 1993, pp. 170-174
Objective-To assess the direct and follow up results of balloon angiop
lasty for aortic recoarctation with respect to the type of initial ope
ration and to determine the midterm effect on systolic blood pressure.
Design-Prospective study of invasive haemodynamic and angiographic da
ta and non-invasive data on upper body blood pressure. Setting-Tertiar
y referral centre for paediatric cardiology. Subjects-24 infants and c
hildren (age 0.3-16.2 years, mean 5.9 years) who had had surgical corr
ection for coarctation (end to end anastomosis (14 patients) subclavia
n flap angioplasty (nine), patch angioplasty (one)). Main outcome meas
ures-Peak systolic gradient over the recoarctation and aortic diameter
s before and directly after angioplasty and at follow up. Upper body b
lood pressure before and after angioplasty and at latest follow up. Re
sults-Mean peak systolic gradient initially decreased from 35 (15) to
12 (9) mm Hg (p < 0.001) and was 9 (10) mm Hg at follow up after 1.4 (
0.5) years. Patients with a subclavian flap repair showed a slight fur
ther decrease in the residual gradient at follow up (p < 0.05). The co
arctation diameter increased from 5.3 (2.6) to 7.7 (2.5) mm (p < 0.001
), and a further increase to 9.3 (2.9) mm (p < 0.01) was present at fo
llow up after 1.4 (0.5) years without significant changes in other aor
tic diameters. Upper body systolic blood pressure decreased from 138 (
24) to 115 (17) mm Hg after balloon angioplasty, and the effect on blo
od pressure persisted at a mean follow up of 3.7 years. One patient di
ed of ventricular failure. Femoral artery thrombosis occurred in three
patients. In one patient a small aneurysm occurred that had not incre
ased at follow up. In one patient restenosis after angioplasty was red
ilated successfully. In one patient dilatation of a residual stenosis
after angioplasty failed. Conclusion-Balloon angioplasty for recoarcta
tion is effective and is associated with accelerated growth of the dil
ated segment at follow up in many patients. The complication rate is a
cceptable. Midterm follow up shows persistent relief of upper body hyp
ertension in most patients.