Na. Fletcher et al., SUCCESSFUL TREATMENT OF CHILDHOOD-ONSET SYMPTOMATIC DYSTONIA WITH LEVODOPA, Journal of Neurology, Neurosurgery and Psychiatry, 56(8), 1993, pp. 865-867
Three patients with childhood onset symptomatic dystonia responded to
levodopa. None fulfilled criteria for a diagnosis of ''dopa responsive
dystonia'' (Segawa's disease). One may have had athetoid cerebral pal
sy for almost 25 years. All obtained dramatic and sustained benefit fr
om levodopa therapy. A therapeutic trial of levodopa is advised in all
patients in whom dystonia has developed in childhood or early adult l
ife, regardless of suspected aetiology or duration of symptoms.