INTRAABDOMINAL PARAGANGLIOMA - CLINICAL, FUNCTIONAL, STRUCTURAL, AND IMMUNOHISTOCHEMICAL STUDY OF AN EXCEPTIONAL CASE

Citation
Jd. Carpeno et al., INTRAABDOMINAL PARAGANGLIOMA - CLINICAL, FUNCTIONAL, STRUCTURAL, AND IMMUNOHISTOCHEMICAL STUDY OF AN EXCEPTIONAL CASE, Revista Clinica Espanola, 193(3), 1993, pp. 127-130
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
00142565
Volume
193
Issue
3
Year of publication
1993
Pages
127 - 130
Database
ISI
SICI code
0014-2565(1993)193:3<127:IP-CFS>2.0.ZU;2-1
Abstract
Paragangliomas are tumors, derived from paraganglionar system, able to synthesize and to liberate substances with neuroregulatory activity. They are rare, mainly in the neck located, difficult to anatomophatolo gic diagnose, and of poor prognosis. They may present as space-occupay ing lesions or as secondary syndromes due to the liberation of biologi cally active substances. Whenever it is possible, surgical excision is the treatment of choice. Nor chemotherapy, nor immunomodulators, like alpha-2b-interferon, have provided satisfactory results. A 57 year-ol d man, with a non-surgical paraganglioma characterized by abdominal ma ss associated with liver and bone metastasis, is presented. The rarity of the intra-abdominal presentation, the image study findings, the hi stophatological and immunohistochemical examinations, and the evolutio n after alpha-2b-interferon therapy are analyzed.