HEMOLYTIC-UREMIC SYNDROME WITH THROMBOTIC MICROANGIOPATHY OF THE RETINA FOLLOWING CYTOMEGALOVIRUS-INFECTION - POSTMORTEM FINDINGS

Haemolytic-uraemic syndrome is characterized by thrombotic microangiop athy of the glomeruli and smaller arterial vessels of the kidney. Extr arenal thrombotic microangiopathy occurs, but ocular involvement is ra rely demonstrated microscopically. We describe a 33 year old woman wit h a 3 week febrile episode and seropositivity for cytomegalovirus infe ction who developed acute renal failure, blindness and severe encephal opathy which was the cause of death. Thrombotic microangiopathy of ret inal vessels may be more common than is expected from the literature. The exclusion of ocular structures in postmortem examinations explains the lack of anatomoclinical correlation.