ARE THERE ESTROGEN-RECEPTORS IN HUMAN LARYNGEAL CANCERS

Authors
NG R GULLANE P CRUKLEY C BANERJEE D KELLEN J
Citation
R. Ng et al., ARE THERE ESTROGEN-RECEPTORS IN HUMAN LARYNGEAL CANCERS, International journal of oncology, 3(1), 1993, pp. 95-98
Citations number
17
Categorie Soggetti
Oncology
Journal title
International journal of oncology → ACNP
ISSN journal
10196439
Volume
3
Issue
1
Year of publication
1993
Pages
95 - 98
Database
ISI
SICI code
1019-6439(1993)3:1<95:ATEIHL>2.0.ZU;2-R
Abstract
The presence of estrogen receptors in laryngeal carcinoma is controver sial; with two independent methods (testing the binding of monoclonal antibodies against receptor protein by immunohistochemistry binding of labelled H-3-estradiol with the charcoal-dextran method), the levels of ER were found to be, if any, extremely low and without correlation to age, sex and previous radiation therapy of the patient. Administrat ion of antiestrogens (if rationalized by the presence of ER) is theref ore not indicated.