The role of endoscopy in NSAID-related gastroduodenal pathologies is r
eviewed, If an accepted and largely used algorithm in which the role o
f endoscopy is exactly identified is not available, current strategy f
or the management of gastroduodenal toxicity gives indication for endo
scopy immediately after the onset of symptoms, anaemia and evidence of
bleeding, overt or occult, The endoscopic patterns of lesions in pati
ents taking NSAID are characteristic patterns of erosive and ulcerativ
e lesions, Endoscopy can recognize early lesions, allowing us to preve
nt a more advanced mucosal damage.