One hundred fifty-two of 399 Crohn's patients (38 percent) diagnosed o
ver 20 years, who lived within a geographically defined area at the ti
me of diagnosis, underwent at least one operation. One hundred seventy
-one resections were performed in 160 operations during a mean follow-
up of 60 months. Forty-eight percent of patients had undergone their f
irst resection within 10 years of diagnosis, and 39 percent of these h
ad undergone a second resection within 10 years of the first. There wa
s no difference between smokers and nonsmokers in the timing of their
surgery.