AFFINITY OF ANTI-GP41 ANTIBODY IN PATIENTS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1

Authors
RADKOWSKI M LASKUS T GOCH A SLUSARCZYK J
Citation
M. Radkowski et al., AFFINITY OF ANTI-GP41 ANTIBODY IN PATIENTS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1, European journal of clinical investigation, 23(8), 1993, pp. 455-458
Citations number
29
Categorie Soggetti
Medicine, Research & Experimental
Journal title
European journal of clinical investigation → ACNP
ISSN journal
00142972
Volume
23
Issue
8
Year of publication
1993
Pages
455 - 458
Database
ISI
SICI code
0014-2972(1993)23:8<455:AOAAIP>2.0.ZU;2-8
Abstract
Anti-gp41 antibody affinity was investigated prospectively in 25 patie nts with asymptomatic and symptomatic HIV-1 infection for a period of 9-42 months. Major differences in the processs of immune response matu ration towards gp41 were observed among individual subjects, however, antibody affinity increased with time in all examined persons includin g patients with AIDS. Anti-gp41 affinity values were found to reflect both the duration and the clinical stage of HIV infection