CAPSAICIN ACTION MODULATES LIPID-PEROXIDATION INDUCED BY DIFFERENT IRRITANTS

Authors
Citation
Ak. De et Jj. Ghosh, CAPSAICIN ACTION MODULATES LIPID-PEROXIDATION INDUCED BY DIFFERENT IRRITANTS, PTR. Phytotherapy research, 7(4), 1993, pp. 273-277
Citations number
34
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
ISSN journal
0951418X
Volume
7
Issue
4
Year of publication
1993
Pages
273 - 277
Database
ISI
SICI code
0951-418X(1993)7:4<273:CAMLIB>2.0.ZU;2-4
Abstract
Capsaicin (8-methyl-n-vanillyl-6-nonenamide), the pungent principle of red hot pepper, has been reported to cause 'activation' followed hy ' desensitization' of the tissue against various types of irritant induc ed damage, on short- and long-term application respectively. This revi ew discusses one aspect of the mechanism of capsaicin induced activati on followed by desensitization by discussing the modulatory effects of capsaicin on lipid peroxidative changes caused by different irritants (e.g. gaseous, chemical and radiation).