INTERACTION OF CAPSAICIN WITH HUMAN ERYTHROCYTE-MEMBRANES

Authors
DE AK SENGUPTA D GHOSH JJ
Citation
Ak. De et al., INTERACTION OF CAPSAICIN WITH HUMAN ERYTHROCYTE-MEMBRANES, PTR. Phytotherapy research, 7(4), 1993, pp. 310-313
Citations number
25
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
7
Issue
4
Year of publication
1993
Pages
310 - 313
Database
ISI
SICI code
0951-418X(1993)7:4<310:IOCWHE>2.0.ZU;2-J
Abstract
Capsaicin (8-methyl-n-vanillyl-6-nonenamide) caused a dose related (1- 100 nM) haemolysis of human red blood cells. This haemolysis was assoc iated with significant changes in erythrocyte membrane lipid component s and acetylcholinesterase (AChE) activity. Ruthenium red blocks this capsaicin-induced haemolysis and membrane AChE activity changes.