Gallbladder agenesis is an extremely rare disease. Necropsy incidence
has been reported to be 0.016%. Failure to locate the gallbladder at t
he time of a planned cholecystectomy can be very challenging. We repor
t such a case during a laparoscopic cholecystectomy. The indication fo
r surgery in these patients are complaints of gallbladder symptoms alo
ng with a false-positive ultrasound study. During exploration, an abno
rmal location of the gallbladder has to be excluded. Ectopic gallbladd
er locations include intrahepatic, lesser omentum, retroperitoneal, re
trohepatic, within the falciform ligament, retroduodenal, and retrohep
atic areas. Thorough exploration and cholangiography are essential. Em
bryologically, the gallbladder and cystic duct arise from the caudal p
ortion of the hepatic bud. All of the previously reported cases of gal
lbladder agenesis have shown an absence of both the gallbladder and cy
stic duct. We report an embryological oddity wherein a patent cystic d
uct was found along with an agenetic gallbladder. This is the first ca
se report of this finding, along with this being the first absent gall
bladder discovered laparoscopically.