GENETIC-EFFECTS OF TRITIUM-LABELED AMINO- ACIDS ON MICE

The frequency of dominant lethal mutations (DLM) in germ cells and the frequency of reciprocal translocations (RT) in spermatogonia of male mice exposed to H-labeled amino acids at the dose of 1.45-2.30 Gy was studied. The effect from H-glycine was equal to that from tritium oxid e (THO). When D,L-lysine-H-3 and L-lysine-H-3 were injected into the b ody of mice the frequency of DLM exceeded that from the equal dose of THO by 2.5 and 7 times, respectively. As to RT, these indexes for H-am ino acids have no statistically significant differences from the simil ar index for THO.