DIFFERENTIATION OF GC-RICH RESTRICTION SI TES IN THE HIGHLY REPEATED DNA IN APODEMUS (MURIDAE, RODENTIA)

nDNAs of six species of wood and field mice of the genus Apodemus (pen insulae, flavicolis, microps, speciosus, and agrarius), grey rat Rattu s norvegicus as well, and house mouse Mus musculus were digested with restriction endonucleases (MspI (CCGG), BspRI (GGCC) and MvaI (CCA/TGG ). Two highly representative satellites are found in A.peninsulae (8%) and M.musculus (20%) genomes using BspRI and MvaI. The length of rest riction fragments of these components are equal to n x 30 and n x 230 nb, respectively. Based on the resuls of PDRF of nDNA in rodent inters pecies, genetic distances are estimated and phylogenetic tree reconstr ucted. Among wood mice examined A.sylvaticus and A.flavicollos are mos t closely related, A.peninsulae is more diverged. Field mouse has appr ox. equal differences from the european and asian species of wood mice . A middle value of genetic distances is about 7.12% in Apodemus genus , 12.69 and 13.2% between Apodemus with M.musculus and R.norvegicus, r espectively.