J. Zahner et Be. Strauer, CA-125 - A TUMOR-MARKER IN LYMPHANGIOLEIO MYOMATOSIS OF DIAGNOSTIC AND PROGNOSTIC IMPORTANCE, Geburtshilfe und Frauenheilkunde, 53(7), 1993, pp. 492-494
Lymphangioleiomyomatosis is a rare tumour of the lymphatic system, aff
ecting mostly women of childbearing age. Due to its rare occurrence, d
iagnosis is mostly made after thorough examination therefor time for a
n early treatment is lost. Diagnostically important are, on the one ha
nd, the histological findings with smooth muscle cells invading the ly
mphatic system, and on the other hand thin-walled cysts in CT scanning
of the lung. CA-125 seems to be a suitable screening parameter for LA
M, which may be additionally of prognostic value. Sensitivity and spec
ificity of CA-125 require further observation.