FINE-NEEDLE ASPIRATION CYTOLOGY OF JUVENILE PAPILLOMATOSIS OF BREAST - A CASE-REPORT

The cytologic findings of juvenile papillomatosis (JP) have been rarel y described. The clinical and cytologic findings were suggestive of a fibroadenoma, but due to the presence of 2 cc of clear fluid during th e aspiration, fibrocystic change was in the differential diagnosis. Op eration and subsequent examination of the mass identified a case of JP (so-called Swiss cheese disease of the breast). Because JP is a marke r for breast carcinoma for the patients' families, and the patients ma y themselves be at increase risk for malignancy, it is important that this entity be considered in the differential diagnosis. The observati ons in this case indicate that it is difficult to diagnose JP only by cytology, but the combination of clinical findings-a well-circumscribe d mass in a young patient with cystic fluid, but with a residual mass after aspiration due to the multicystic nature of JP-with the cytologi c findings-sheets of hyperplatic breast epithelium with areas resembli ng fibroadenoma, macrophages, and apocrine cells-that appear to be suf ficiently characteristic to suggest the diagnosis of JP. (C) 1993 Wile y-Liss, Inc.