A comparison of the adverse effects of the depot Preparations of flupe
nthixol decanoate (Depixol(R)) and fluphenazine decanoate (Modecate(R)
) was conducted in 100 chronic schizophrenic patients attending the ou
tpatient department at the Psychiatric Hospital, Bahrain. Although aka
thisia, parkinsonism, weight pin and endocrine effects were seen in a
large number of cases, there was no statistically significant differen
ce in their incidence between the 2 groups. Furthermore, there was no
difference in the efficacy of the 2 preparations studied. We observed
abnormal hair loss in 42 cases - 22 on Depixol(R) and 20 on Modecate(R
). This previously unreported side effect is probably due to these lon
g-acting antipsychotic drugs.