Patients with facial pain, without Overt dental disease, are often see
n in both medical and dental practice. The differential diagnosis incl
udes (a) cluster headache, in which patients have severe unilateral pa
ins lasting 30 to 120 minutes that respond to verapamil, corticosteroi
ds or lithium; (b) migraine, in which attacks are longer and are often
accompanied by nausea and visual disturbance, and can be managed usin
g anti-inflammatory analgesics, with or without metoclopramide, or sum
atriptan, although frequent attacks are best suppressed by continuous
propranolol or pizotifen; (c) trigeminal neuralgia, knifelike unilater
al pains usually responsive to carbamazepine; and (d) temporal arterit
is, a steadier pain very responsive to corticosteroids. There is no ev
idence that continuous 'idiopathic facial pain' is a result of maloccl
usion (i.e. the way in which the teeth fit together), and its aetiolog
y remains obscure, although there is some biochemical evidence linking
it to depression. Many patients respond to simple analgesia and firm
reassurance from the physician, although antidepressant therapy (e.g.
nortriptyline or dothiepin) is often of great value.