Jm. Desbordes et al., A MULTICENTRIC RETROSPECTIVE STUDY OF THE PREVENTION OF THROMBOEMBOLIC COMPLICATIONS AFTER LUMBAR DISKECTOMY, Neuro-chirurgie, 39(3), 1993, pp. 178-181
A retrospective study of thromboembolic complications after lumbar dis
c surgery has been performed. It included 16656 patients from fifty ne
urosurgical units, operated on over the year 1989. The average number
of operations was 333 +/- 19,5 in each unit, their average duration 55
,2 +/- 20 minutes, and the hospital care 6,2 +/- 1,7 days. Surgery was
performed using the genupectoral position in 64 % of the cases, the s
upine position in 28 %, and the lateral position in 8 %. Two groups of
patients have been individualized: a first group of patients with no
preventive antithrombic treatment (46 % of the units) including 10 351
patients, a second group (54 % of the units) including 6 305 patients
and receiving a systematic treatment with low molecular weight hepari
n (4 304 patients) or calciparin (1 001 patients) or antiplatelet agen
ts or pentosane polysulfate (I 000 patients). 0,63 % of the patients (
105) had a thromboembolic accident : 0,65 % in the first group (68 cas
es) and 0,58 % in the second (37 cases). No statiscally significant di
fference was noticed between the two groups concerning pulmonary embol
ism and/or lower-limb thrombophlebitis. Nevertheless, a prospective ra
ndomized study would be usefull to corroborate this first data.