Five cases of unilateral intracranial internal carotid artery (ICA) oc
clusion received both carotid angiographic and ultrasonographic studie
s. The Doppler examination showed that the resistive index (RI) of the
common carotid artery (CCA) and ICA was higher but the peak systolic
velocity was lower on the diseased side as compared with the normal si
de. Absence of the diastolic phase was found in the CCA flow in 2 case
s and in the ICA flow in 3 cases on the diseased side. The mean CCA fl
ow volume on the diseased side (271+/-82 mL/min) was half or less than
that on the normal side (680+/-86 mL/min) (P < 0.01). The flow volume
of the diseased ICA (49+/-20 mL/min) was markedly lower than that of
the normal side (344+/-49 mL/min) (P < 0.01) and was also less than th
at of the ipsilateral external carotid artery (ECA) (129+/-43 mL/min).
The Doppler ophthalmic artery flow all showed a forward direction. Th
e authors propose that the following extracranial carotid ultrasonogra
phic findings may be helpful in the prediction of intracranial carotid
artery occlusion: (1) diminished frequencies, increased RI, and a mor
e than 50% reduction of flow volume in the CCA as compared with the op
posite side; (2) diminished frequencies to loss of the diastolic phase
, a more than 50% reduction of the flow volume, and reversed ICA/ECA f
low volume in the ICA as compared with the opposite side; and (3) a fo
rward Doppler ophthalmic artery flow.