Laparoscopic surgery is very popular among physicians and patients bec
ause this technique is associated with safety, shorter hospital stay,
early return to normal activity, and cosmetic acceptance of the operat
ive scar. Although the procedure involves minimal invasion and tissue
damage, it has potentially serious complications, including cardiopulm
onary effects that result mainly from hypercarbia and raised intraabdo
minal pressure caused by pneumoperitoneum. Absorbed carbon dioxide fro
m the peritoneal cavity tends to cause acidosis. Leakage of the gas in
to tissue spaces may induce subcutaneous emphysema, pneumothorax, pneu
momediastinum and pneumopericardium. Cardiac effects include arrhythmi
as, hypotension, cardiac arrest, gas embolism, pulmonary edema, and my
ocardial ischemia or infarction. Some of these effects, though rare, a
re serious and potentially fatal. Physicians should anticipate these p
roblems in their patients undergoing laparoscopic procedures. This rev
iew discusses the technique of and physiologic considerations in lapar
oscopic surgery as well as its potential complications.