G. Lebouthillier et al., TC-99M SESTAMIBI AND OTHER AGENTS IN THE DETECTION OF METASTATIC MEDULLARY CARCINOMA OF THE THYROID, Clinical nuclear medicine, 18(8), 1993, pp. 657-661
The 10-year survival rate for medullary carcinoma of the thyroid (MCT)
is 50%; thus, good tumor-seeking radiopharmaceuticals are needed to l
ocalize foci of recurrence and metastasis during follow-up. Two patien
ts with metastatic MCT were studied with Tl-201, I-131 MIBG, Tc-99m (V
)-DMSA, and Tc-99m MIBI. A SPECT study with the latter agent allowed t
he visualization and precise localization of a metastatic mediastinal
lymph node. More studies need to be done to evaluate the role of Tc-99
m MIBI in the detection of recurrence and metastases of MCT.