Contact diode laser microvascular anastomosis appears to be a valuable
technique for anastomosing small arteries and veins. Significantly le
ss foreign body reaction and markedly decreased operative time has bee
n shown to be a major advantage of using contact diode laser technolog
y. The authors have found that contact diode laser anastomosis can be
performed in vessels as small as 1 mm in size using a 200-mum flat tip
synthetic sapphire probe. Light microscopy has shown a significant de
crease in foreign body reaction at the level of the anastomosis using
laser techniques as compared to standard vessel anastomosis with 10-0
nylon sutures. The role of fibronectin and changes in collagen associa
ted with laser anastomosis were also explored. Light microscopic elect
ron-microscopic results as well as biotin-avidin immunoperoxidase fibr
onectin studies will be discussed.