STUDY ON THE SYNTHESIS AND CHARACTERIZATION OF NOVEL IMMOBILIZED BETA-CYCLODEXTRIN POLYMER .1.

A series of novel beta-cyclodextrin polymers was synthesized by immobi lization of beta-cyclodextrin on the chloromethylated crosslinked poly styrene carriers. The synthetic conditions such as reaction time, temp erature, molar feeding ratio of reactants, the degree of crosslinking of polystyrene and the catalysts used were studied in detail and the c hemical and physical structures of the formed beta-CDpolymers were cha racterized. Results show that the preparation method is simple and the amount of beta-CD immobilized is high. As biomedical adsorbents, they were tested for removal of various endogenous and exogenous toxins su ch as phenols, aromatic amins, barbitals and unconjugated bilirubin. R esults indicate that the adsorption capacity for those toxins can be e nhanced by the inclusion interaction among the beta-CD, the substrate molecules and the beta-CD polymers.