BACTERIA AS PROTEIN CARRIERS IN AGGLUTINATION ASSAYS

We report here the application of bacteria Brucella abortus as a parti culare solid support that can be used as a protein carrier. Carbohydra te unitis of the bacterial surface were oxidised with NaIO4 and human IgG molecules were covalently boud to the bacterial surface. Bacteria coated with human IgG were allowed to react with sheep anti human IgG serum in an agglutination assay. The results of the agglutination test confirmed that satisfactory activition of the bacterial and immobiliz ation of human IgG can be achieved.