C. Perrin et al., HORNY PERIFOLLICULAR MUCINOSIS - AN ATYPICAL PITYRIASIS-RUBRA PILARIS-LIKE ERUPTION ASSOCIATED WITH HIV-INFECTION, The American journal of dermatopathology, 15(4), 1993, pp. 358-362
We present a case of pityriasis rubra pilaris (PRP)-like eruption, in
association with human immunodeficiency virus (HIV) infection, clinica
lly characterized by follicular papules with some elongated spines and
comedo-like lesions. The lesions were located on the back, flanks, an
d proximal extremities. Orthokeratotic follicular plugs and perifollic
ular mucinous degeneration were consistently observed on three biopsie
s. The most characteristic histological features of PRP were absent. T
o our knowledge, this is the first reported case of this kind. Such a
case could suggest an atypical PRP modified by HIV infection. It is al
so possible that it represents a new entity associated with advanced H
IV infection (horny perifollicular mucinosis).