I. Gomezorellana et D. Hallen, THE THERMODYNAMICS OF THE BINDING OF BENZENE TO BETA-CYCLODEXTRIN IN AQUEOUS-SOLUTION, Thermochimica acta, 221(2), 1993, pp. 183-193
The apparent enthalpies, entropies and Gibbs energies for the binding
of benzene to beta-cyclodextrin in aqueous solution have been determin
ed at 291.15, 298.15 and 308.15 K by microcalorimetry. The calorimetri
c data are consistent with a binding model that assumes formation of b
oth 1:1 and 2:1 (benzene:beta-cyclodextrin) adducts. The apparent chan
ge in heat capacity for the 1:1 binding, calculated from the temperatu
re derivative of the enthalpy changes, indicates that the hydrophobic
effect is the driving force for formation and stability of this comple
x.