Male rats and pregnant and nonpregnant female rats of the Wistar strai
n were sham-exposed or exposed to static (0.49 T) or to extremely low
frequency (50 Hz) magnetic fields (0.018 T) 2 h per day for 20 consecu
tive days. Measures of irritability, exploratory activity, and locomot
ion were made in that order before and after the 4th, 10th, and 17th 2
-h exposures. A reliable decrease in the irritability of rats after re
peated exposure to a static or undulating field was found. No signific
ant effects of treatment conditions on open-field behavior and locomot
or activity were observed. Pregnancy had no influence on the behaviora
l end points. These results indicate that irritability of rats may be
used as a simple behavioral indicant of mammalian sensitivity to magne
tic fields. (C) 1993 Wiley-Liss, Inc.