NON-BIOMIMETIC OXIDATION OF 1,4-DIHYDROPYRIDINES

Authors
LAVILLA R GULLON F BARON X BOSCH J
Citation
R. Lavilla et al., NON-BIOMIMETIC OXIDATION OF 1,4-DIHYDROPYRIDINES, Chemical communications, (2), 1997, pp. 213-214
Citations number
27
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
2
Year of publication
1997
Pages
213 - 214
Database
ISI
SICI code
1359-7345(1997):2<213:NOO1>2.0.ZU;2-E
Abstract
The reaction between N-alkyl-1,4-dihydropyridines and dimethyldioxiran e leads to dimeric tetrahydropyridines having oxygen atoms at the 2- a nd 3-positions in good yields and with good stereocontrol; these compo unds are useful iminium ion precursors, and are satisfactorily transfo rmed into 2-substituted 3-hydroxy-1,2,3,4-tetrahydropyridines.