N-METHYLIDENE[BIS(TRIMETHYLSILYL)METHYL]AMINE - THE FIRST ISOLABLE AND STABLE MONOMERIC METHANIMINE ALLOWING THERMAL [2+2] CYCLOADDITIONS WITH KETENES

Authors
PALOMO C AIZPURUA JM LEGIDO M GALARZA R
Citation
C. Palomo et al., N-METHYLIDENE[BIS(TRIMETHYLSILYL)METHYL]AMINE - THE FIRST ISOLABLE AND STABLE MONOMERIC METHANIMINE ALLOWING THERMAL [2+2] CYCLOADDITIONS WITH KETENES, Chemical communications, (2), 1997, pp. 233-234
Citations number
29
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
2
Year of publication
1997
Pages
233 - 234
Database
ISI
SICI code
1359-7345(1997):2<233:N-TFIA>2.0.ZU;2-P
Abstract
N-Methylidene[bis(trimethylsilyl)methyl]amine acts as a stable methani mine synthon [CH2=NH] equivalent in [2 + 2] cycloadditions to ketenes, generated from acid chlorides and triethylamine, to provide 4-unsubst ituted beta-lactams in a single step.