Mp. Revel et al., MAGNETIC-RESONANCE-IMAGING OF THE FETUS - A STUDY OF 20 CASES PERFORMED WITHOUT CURARIZATION, Prenatal diagnosis, 13(9), 1993, pp. 775-799
Twenty patients underwent magnetic resonance imaging (MRI) at a mean g
estational age of 32 weeks. There were 12 patients with suspected feta
l brain abnormality and four with intrauterine growth retardation (IUG
R), while the remaining four cases were studied for other reasons. The
MRI examinations were performed on a 0.5 Tesla machine, with surface
coils. One minute acquisition time T1 sequences were used. All the stu
dies were performed without fetal curarization. and only under materna
l sedation using flunitrazepam given per os 1 h before MRI examination
. Three examinations were incomplete because of fetal movement artefac
ts. In the remaining cases, MRI allowed the examination of fetal brain
anatomy. In five cases, it helped to differentiate iso at d hydroceph
alus and corpus callosum agenesis. Sub-ependymal nodules were depicted
in a case of fetal tuberous sclerosis. One suspected arachnoid cyst w
as proved to be an ultrasound artefact. Decreased fetal fat on MR imag
es was correlated with low birth weight in cases of IUGR. Due to its b
etter spatial resolution, ultrasonography was more accurate for the di
agnosis of facial and lumbar anomalies. Fetal MRI may be performed wit
hout curarization. Surface coils allow the detailed analysis of brain
parenchyma, and thus MRI is especially useful in the difficult prenata
l diagnosis of fetal brain abnormalities.