APPLICATION OF FLUORESCENT IN-SITU HYBRIDIZATION FOR DE-NOVO ANOMALIES IN PRENATAL-DIAGNOSIS

Authors
VANOPSTAL D EUSSEN HJ VANHEMEL JO SACHS ES
Citation
D. Vanopstal et al., APPLICATION OF FLUORESCENT IN-SITU HYBRIDIZATION FOR DE-NOVO ANOMALIES IN PRENATAL-DIAGNOSIS, Prenatal diagnosis, 13(9), 1993, pp. 825-832
Citations number
21
Categorie Soggetti
Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
13
Issue
9
Year of publication
1993
Pages
825 - 832
Database
ISI
SICI code
0197-3851(1993)13:9<825:AOFIHF>2.0.ZU;2-2
Abstract
Fluorescent in situ Hybridization (FISH) was carried out for three cas es of abnormal karyotypes in prenatal studies. Two concerned de novo s tructural anomalies and the third a marker chromosome. The origin of t he extra material could be defined in all three cases, which gives a b etter insight into the relationship between genotype and phenotype and makes more adequate genetic counselling possible.