CLINICAL-EVALUATION OF A RAPID IMMUNOINHIBITION ASSAY FOR CREATINE KINASE-MB IN SUSPECTED MYOCARDIAL-INFARCTION

We examined the clinical performance of a new immunoinhibition assay ( INH) for the measurement of creatine kinase isoenzyme MB (CK-MB). In 1 96 consecutive patients admitted for exclusion of acute myocardial inf arction, serial blood samples were evaluated by INH, immunoradiometric assay (IRMA), and electrophoresis (ELP). Using receiver operating cha racteristic curve analysis, the diagnostic performance of the INH assa y was comparable to IRMA and ELP. As compared with these alternative m ethodologies, this newly available INH assay for CK-MB provides simila r diagnostic accuracy and increased convenience at a greatly reduced c ost.