FURTHER DEVELOPMENTS IN METAL-CATALYZED C-C BOND-CLEAVAGE IN ALLYLIC DIMETHYL MALONATE DERIVATIVES

Authors
BRICOUT H CARPENTIER JF MORTREUX A
Citation
H. Bricout et al., FURTHER DEVELOPMENTS IN METAL-CATALYZED C-C BOND-CLEAVAGE IN ALLYLIC DIMETHYL MALONATE DERIVATIVES, Tetrahedron letters, 38(6), 1997, pp. 1053-1056
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
6
Year of publication
1997
Pages
1053 - 1056
Database
ISI
SICI code
0040-4039(1997)38:6<1053:FDIMCB>2.0.ZU;2-I
Abstract
The use of a catalytic amount of nickelbis(1,4-bis(diphenylphosphino)b utane) in DMF enables the activation of the C-C bond in dimethyl allyl malonate derivatives to proceed under rather smooth reaction condition s, without added nucleophile. Several examples like isomerization of s ubstituted-allyl malonate derivatives, racemization of chiral products , but also a synthetic application as an inverse disproportionation re action are described. (C) 1997, Elsevier Science Ltd.