Jg. Pirofsky et al., SPINAL OSTEOMYELITIS DUE TO MYCOBACTERIUM-AVIUM-INTRACELLULARE IN AN ELDERLY MAN WITH STEROID-INDUCED OSTEOPOROSIS, Spine (Philadelphia, Pa. 1976), 18(13), 1993, pp. 1926-1932
Disseminated mycobacterial infections are becoming widely appreciated
among immunosuppressed and debilitated persons. Specific microbiologic
diagnosis may take several weeks, requiring empiric therapy in the in
terim. A case of an elderly man undergoing steroid treatment who devel
oped spinal osteomyelitis initially thought to be caused by Mycobacter
ium tuberculosis is described. He was eventually shown to have infecti
on due to M. avium-intracellulare, which requires a different therapeu
tic approach. The importance of considering atypical mycobacteria in s
ystemic infections and the value of aggressive antimicrobial therapy i
n conjunction with a comprehensive rehabilitation program during hospi
talization are emphasized in order to provide optimal management and p
revent further disability.