NICOTINAMIDE AND CARBOGEN - MAJOR EFFECT ON THE RADIOSENSITIVITY OF EMT6 AND HRT18 TUMORS

Authors
SIMON JM LARTIGAU E GUICHARD M
Citation
Jm. Simon et al., NICOTINAMIDE AND CARBOGEN - MAJOR EFFECT ON THE RADIOSENSITIVITY OF EMT6 AND HRT18 TUMORS, Radiotherapy and oncology, 28(3), 1993, pp. 203-207
Citations number
28
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Journal title
Radiotherapy and oncology → ACNP
ISSN journal
01678140
Volume
28
Issue
3
Year of publication
1993
Pages
203 - 207
Database
ISI
SICI code
0167-8140(1993)28:3<203:NAC-ME>2.0.ZU;2-Q
Abstract
The effect of nicotinamide and/or carbogen breathing on the response o f EMT6 and HRT18 tumours, irradiated in vivo, was evaluated using an i n vitro colony assay. In the single dose schedules, the most efficient treatment was carbogen plus nicotinamide compared to air breathing mi ce. In a fractionated regime carbogen plus nicotinamide increased also response to radiation.