Rw. Laing et al., STEREOTAXIC RADIOTHERAPY OF IRREGULAR TARGETS - A COMPARISON BETWEEN STATIC CONFORMAL BEAMS AND NONCOPLANAR ARCS, Radiotherapy and oncology, 28(3), 1993, pp. 241-246
Citations number
25
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Stereotactic radiotherapy using a linear accelerator is usually equate
d with the technique of delivery using multiple non-coplanar arcs, whi
ch achieves a spherical dose distribution. As the majority of intracra
nial lesions are not spherical, a range of schematized tumour shapes w
ere planned to assess the role of static conformal beams in the treatm
ent of irregular lesions. A sphere and 2 ellipsoids, ranging from 20 t
o 50 mm maximum diameter located intracranially were planned using 3,
4, and 6 non-coplanar static beams with conformal blocks and were comp
ared with four 120-degrees non-coplanar arcs. Comparison of the plans
was made by the relative sparing of normal tissue outside the target v
olume using three-dimensional dose-volume distributions. Non-coplanar
arcs spared more normal tissue at low isodoses and achieved the best h
igh dose sparing for spherical targets. For the majority of irregular
targets, 3 and 4 static beams spared more tissue at doses greater-than
-or-equal-to 50% and greater-than-or-equal-to 80% than the arc techniq
ue. For all irregular volumes, maximum sparing of normal tissue to iso
doses greater-than-or-equal-to 50% and greater-than-or-equal-to 80% of
the treatment isodose was obtained with 6 static conformal beams. We
conclude that irregularly shaped tumours suitable for stereotactic rad
iotherapy with a linear accelerator are better treated with conformal
static non-coplanar beams rather than with the multiple arc technique.