THE EFFECT OF DICHLORVOS AND POLYCHLORINATED-BIPHENYLS (DELOR 103) ONTHE PROTOZOAN TETRAHYMENA-PYRIFORMIS

The effect of dichlorvos and polychlorinated biphenyls on the protozon Tetrahymena pyriformis was studied. Both xenobiotics were of high tox icity in the used test-object and have caused significant changes in t he activity of the observed enzymes. Dichlorvos has decreased the acti vity acetylcholine esterase by about 80 %. At the concentration of 15. 0 mg.l-1 a significant decrease of ALT activity was also observed afte r 90 and 240 minutes of incubation and a significant decrease of LDH a ctivity occurred after 240 minutes of incubation. Polychlorinated biph enyls have increased the activity of aminotransferases and alkaline ph osphatase, respectively. The activity of lactate dehydrogenase as comp ared with the control was markedly lower.