CONSTRUCTION OF A MAPPING PANEL OF HUMAN- RODENT HYBRID-CELLS

Authors
KOPANTZEV EP NESTEROVA TB BORODIN AM ZAKIAN SM
Citation
Ep. Kopantzev et al., CONSTRUCTION OF A MAPPING PANEL OF HUMAN- RODENT HYBRID-CELLS, Genetika, 29(9), 1993, pp. 1440-1452
Citations number
23
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
29
Issue
9
Year of publication
1993
Pages
1440 - 1452
Database
ISI
SICI code
0016-6758(1993)29:9<1440:COAMPO>2.0.ZU;2-V
Abstract
A clone panel of 27 human-Chinese hamster and 4 human-mouse somatic ce ll hybrids which contained as minimum five discriminating clones for a ny chromosome pairs was set up. Segregation analysis of 45 human chrom osome-specific isoenzymes and PCR markers in hybrid clones allowed to demonstrate a possibility to apply the obtained panel for chromosome m apping of human genes.