For the first time, the karyotypes of three species of the family Echi
myidae from two localities of Peru - Dactylomys dactylinus, Lonchothri
x emiliae, Proechimys sp. are described. D. dactylinus has the highest
diploid number in mammals - 2n = 94, NF = 144. The chromosomes includ
e 25 pairs of meta- and submetacentrics and 22 pairs of acrocentrics.
Heterochromatin is found in the centromeric regions in one pair of sub
metacentric, 3 pairs of metacentrics and 19 pairs of acrocentrics. L.
emiliae - 2n = 60, NF = 116. The chromosomes include 28 pairs of meta-
and submetacentrics and 2 pairs of small acrocentrics. Constitutive h
eterochromatin is confined in the centromeric regions of the majority
of chromosomes Proechimys sp. - 2n = 34, NFa = 56. The autosomes compl
ement includes one pair of large submetacentrics, 10 pairs of medium-s
ized small metacentrics and submetacentrics, one pair of large subtelo
centrics and four pairs of acrocentrics. The X-chromosome is a medium-
sized acrocentric and the Y is a small acrocentric. Constitutive heter
ochromatin is confined in the centromeric regions of 10 pairs autosome
s. Comparison of the chromosomes stained by G-banding revealed the mai
n reconstruction of chromosomes in the species studied that has greatl
y changed the degree of homoeology.