GENETIC-ANALYSIS OF THE RESTING EEG PARAM ETERS OF SCHIZOPHRENICS ANDTHEIR RELATIVES

Citation
Vi. Trubnikov et al., GENETIC-ANALYSIS OF THE RESTING EEG PARAM ETERS OF SCHIZOPHRENICS ANDTHEIR RELATIVES, Genetika, 29(9), 1993, pp. 1519-1525
Citations number
15
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00166758
Volume
29
Issue
9
Year of publication
1993
Pages
1519 - 1525
Database
ISI
SICI code
0016-6758(1993)29:9<1519:GOTREP>2.0.ZU;2-0
Abstract
The heritability of the resting EEG parameters was studied in 45 schiz ophrenic families. In offspring - parent pairs (N = 94) and sibs pairs (N = 27) high correlation of average power values of frequency bands between relatives was found (r > 0,5 for alpha and beta power; r 0,2 t o 0,45 for delta and theta power in different electrode placement). Li near discriminate functions (LDF) to separate 1) a control group (N = 20) from healthy relatives (N = 46), 2) control group from relatives w ith borderline pathology (N = 36) and 3) healthy relatives from relati ves with borderline pathology were obtained. True classification is po ssible in 79%, 81% and 76% cases, heritability coefficients of LDF are 47,7, 64,6 and 57,1% respectively.