M. Oshima et al., MYOCARDIAL SPECT AND LEFT-VENTRICULAR PERFORMANCE STUDY USING A SINGLE TC-99M TEBOROXIME INJECTION - COMPARISON WITH TL-201 MYOCARDIAL SPECT, Clinical nuclear medicine, 18(10), 1993, pp. 844-851
Myocardial SPECT using teboroxime was compared to thallium SPECT in 26
patients undergoing cardiac catheterization. Agreement between thalli
um SPECT and teboroxime SPECT for the identification of myocardial seg
ments was 209/235 (89%). A significant correlation was found in 15 pat
ients between the left ventricular ejection fraction by teboroxime fir
st-pass study and the ejection fraction by contrast ventriculography.
In nine patients with myocardial infarction and/or multivessel coronar
y artery disease, the ejection fraction revealed a mean decrease from
0.52 at rest to 0.46 at exercise. Teboroxime makes it possible to perf
orm an exercise first-pass study of left ventricular ejection fraction
followed by myocardial perfusion imaging.